|
| 產(chǎn)地 | 進(jìn)口、國產(chǎn) |
| 品牌 | 上海莼試 |
| 保存條件 | Store at -20 °C |
| 貨號(hào) | CS11666 |
| 應(yīng)用范圍 | WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 Flow-Cyt=1:100-500 ICC=1:100-500 IF=1:50-200 |
| CAS編號(hào) | |
| 抗體名 | Anti-TSPAN5 |
| 克隆性 | |
| 靶點(diǎn) | 詳見說明書 |
| 適應(yīng)物種 | 詳見說明書 |
| 形態(tài) | 詳見說明書 |
| 宿主 | 詳見說明書 |
| 亞型 | IgG |
| 標(biāo)識(shí)物 | 詳見說明書 |
| 濃度 | 1mg/1ml% |
| 免疫原 | KLH conjugated synthetic peptide derived from human TSPAN5 |
技術(shù)外包服務(wù):
★四分子交聯(lián)體5抗體（四旋蛋白）規(guī)格 分子生物學(xué)：質(zhì)粒抽提、PCR、Q-PCR、RT-PCR、分子生物學(xué)：基因合成、引物合成、基因測序、載體構(gòu)建等
★蛋白工程：原核、哺乳動(dòng)物蛋白表達(dá)系統(tǒng)等
★病毒包裝：腺病毒、慢病毒等
★抗體工程：磁珠分選、病理染色、WB、ELISA、IP、IF、IHC、FACS、Confocal等等
★細(xì)胞工程：細(xì)胞表型分析(凋亡、增殖、周期、遷移、侵襲、修復(fù)、克隆形成)、細(xì)胞培養(yǎng)、細(xì)胞膜制備、穩(wěn)定細(xì)胞株構(gòu)建、細(xì)胞RNAi技術(shù)等等。
實(shí)驗(yàn)流程：
四分子交聯(lián)體5抗體（四旋蛋白）規(guī)格 英文名稱 Anti-TSPAN5
中文名稱 四分子交聯(lián)體5抗體（四旋蛋白）規(guī)格
別 名 NET 4; NET-4; TSPAN 5; NET4; Tetraspan 5; Tetraspan NET 4; Tetraspan NET-4; Tetraspan TM4SF; Tetraspanin 5; Tetraspanin-5; Tetraspanin5; TM4SF9; Transmembrane 4 superfamily member 8; Transmembrane 4 superfamily member 9; TSN5_HUMAN; Tspan-5; TSPAN5.
產(chǎn)品屬性：
濃 度 1mg/1ml
規(guī) 格 0.2ml/200μg
抗體來源 Rabbit
克隆類型 polyclonal
交叉反應(yīng) Human, Mouse, Rat
產(chǎn)品類型 一抗
研究領(lǐng)域 細(xì)胞生物 神經(jīng)生物學(xué) 信號(hào)轉(zhuǎn)導(dǎo) 干細(xì)胞 通道蛋白 細(xì)胞分化 細(xì)胞骨架 細(xì)胞外基質(zhì)
蛋白分子量 predicted molecular weight: 57kDa
性 狀 Lyophilized or Liquid
免 疫 原 KLH conjugated synthetic peptide derived from human TSPAN5
亞 型 IgG
純化方法 affinity purified by Protein A
儲(chǔ) 存 液 Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4
四分子交聯(lián)體5抗體（四旋蛋白）規(guī)格 產(chǎn)品應(yīng)用 WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 Flow-Cyt=1:100-500 ICC=1:100-500 IF=1:50-200
（石蠟切片需做抗原修復(fù)）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Important Note This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
產(chǎn)品介紹 NET-4, also known as TSPAN5 or TM4SF9, is a 268 amino acid multi-pass membrane protein that belongs to the tetraspanin family and is thought to play a role in signal transduction events related to cell development, activation, growth and motility. The gene encoding NET-4 maps to human chromosome 4, which encodes nearly 6% of the human genome and has the largest gene deserts (regions of the genome with no protein encoding genes) of all of the human chromosomes. Defects in some of the genes located on chromosome 4 are associated with Huntington's disease, Ellis-van Creveld syndrome, methylmalonic acidemia and polycystic kidney disease.
Function : DNA-binding protein that specifically binds heat shockpromoter elements (HSE) and activates transcription. In highereukaryotes, HSF is unable to bind to the HSE unless the cells areheat shocked.
Subunit : Monomer. Under normal conditions, interacts with HSP90AA1in the HSP90 multichaperone complex; the interaction preventstrimerization and activation of HSF1. On activation by heat-stressor by other factors such as metal ions, HSF1 is released from thecomplex, homotrimerizes, is hyperphosphorylated and translocated tothe nucleus where, subsequently, it can activate transcription.Binds the complex through the regulatory domain. Interacts withSYMPK and CSTF2 in heat-stressed cells. Interacts with FKBP4 in theHSP90 multichaperone complex; the interaction is independent of thephosphorylation state of HSF1. Interacts with MAPKAPK2.
Subcellular Location : Membrane; Multi-pass membrane protein (Probable).
Post-translational modifications : Phosphorylated on multiple serine residues, a subset of whichare involved in stress-related regulation of transcriptionactivation. Constitutive phosphorylation represses transcriptionalactivity at normal temperatures. Levels increase on specificresidues heat-shock and enhance HSF1 transactivation activity.Phosphorylation on Ser-307 derepresses activation on heat-stressand in combination with Ser-303 phosphorylation appears to beinvolved in recovery after heat-stress. Phosphorylated on Ser-230by CAMK2, in vitro. Cadmium also enhances phosphorylation at thissite. Phosphorylation on Ser-303 is a prerequisite for HSF1sumoylation. Phosphorylation on Ser-121 inhibits transactivationand promotes HSP90 binding. Phosphorylation on Thr-142 alsomediates transcriptional activity induced by heat.
Sumoylated with SUMO1 and SUMO2 on heat-shock. Heat-induciblesumoylation occurs after 15 min of heat-shock, after which levelsdecrease and at 4 hours, levels return to control levels.Sumoylation has no effect on HSE binding nor on transcriptionalactivity. Phosphorylation on Ser-303 is a prerequisite forsumoylation.
Similarity : Belongs to the tetraspanin (TM4SF) family.
Database links : UniProtKB/Swiss-Prot: P62079.1
全、新、優(yōu)、品、好四大特點(diǎn)：
四分子交聯(lián)體5抗體（四旋蛋白）規(guī)格 全：公司提供上萬種產(chǎn)品，涵蓋了生物試劑，elisa試劑盒，標(biāo)準(zhǔn)品，培養(yǎng)基，原裝耗材，抗體、培養(yǎng)基、ATCC細(xì)胞等，基本上各種科研所需產(chǎn)品在我司都能找到。
新：產(chǎn)品更新速度較快，基本上每周都有新產(chǎn)品出現(xiàn)。
優(yōu)：產(chǎn)品質(zhì)量好，投訴比較少。
好：我公司具有優(yōu)質(zhì)的技術(shù)團(tuán)隊(duì)，產(chǎn)品一旦售出，實(shí)驗(yàn)過程中遇到困難可提供在線技術(shù)咨詢。使您使用產(chǎn)品時(shí)沒有任何的后顧之憂。
正在熱銷的相關(guān)產(chǎn)品：
Anti-SPHK1/FITC 熒光素標(biāo)記鞘氨醇激酶1抗體IgGMulti-class antibodies規(guī)格： 0.2ml
TIMP-1(Tissue Inhibitor of Metalloproteinase-1) 金屬蛋白酶組織抑制因子-1(抗原)Multi-class antibodies規(guī)格： 0.5mg
相關(guān)基因抗體 Anti-PADI4/PAD4 0.1ml
SAP62 英文名稱： 剪接體相關(guān)蛋白62抗體 0.2ml
EIF2C 英文名稱： 真核翻譯起始因子2C1抗體 0.2ml
Rhesus antibody Rh Phospho-NFKB1(Ser893) 磷酸化細(xì)胞核因子p50/k基因結(jié)合核因子抗體 規(guī)格 0.1ml
TIMP-1(Tissue Inhibitor of Metalloproteinase-1) 金屬蛋白酶組織抑制因子-1(抗原)Multi-class antibodies規(guī)格： 0.5mg
FoxP1(Forkhead box P1) FoxP1(T細(xì)胞轉(zhuǎn)錄因子)抗原Multi-class antibodies規(guī)格： 0.5mg
CCNA1 Cyclin A1 / CCNA1 鼠單抗 (PE) Human
Rhesus antibody Rh phospho-Dnmt1(Ser154) 磷酸化DNA甲基轉(zhuǎn)移酶1抗體 規(guī)格 0.1ml
雜交袋(15×25cm) 100張/包 國產(chǎn)
ZFYVE27 英文名稱： 鋅指FYVE結(jié)構(gòu)域蛋白27抗體 0.2ml
DIAPH2 英文名稱： DIAPH2蛋白抗體 0.2ml
CCNA1 Cyclin A1 / CCNA1 鼠單抗 (PE) Human
Plg (Rabbit Plasminogen) ELISA Kit 兔子纖溶酶原Multi-class antibodies規(guī)格： 96T
Anti-CXCR3/CD183(rat,mo) /FITC 熒光素標(biāo)記兔抗大、小鼠細(xì)胞表面趨化因子受體3抗體IgGMulti-class antibodies規(guī)格： 0.2ml
Rhesus antibody Rh DBF4B/ASKL1 S期激酶活化蛋白DBF4B抗體 規(guī)格 0.2ml
Monkey IgG/PE 熒光素PE標(biāo)記猴IgG 0.1ml
Beta-lactoglobulin 英文名稱： β-乳球蛋白抗體 1ml
Rhesus antibody Rh β-Amyloid 1-42(CT) β淀粉樣肽1-42 (C端)抗體 規(guī)格 0.1ml
Anti-CXCR3/CD183(rat,mo) /FITC 熒光素標(biāo)記兔抗大、小鼠細(xì)胞表面趨化因子受體3抗體IgGMulti-class antibodies規(guī)格： 0.2ml
人包蟲抗體IgG ELISA 試劑盒 96T/48T 試劑盒 組裝/原裝
兔子游離脂肪酸(FFA)免疫試劑盒 Rabbit Free Fatty Acids,FFA ELISA Kit
水通道蛋白2(AQP-2)ELISA試劑盒 ，英文名： AQP-2 ELISA Kit
Plahormoneabscisicacid,ABAELISA試劑盒植物激素脫落酸(ABA)ELISA試劑盒規(guī)格：96T/48T
GuineapigleukoieneD4,LT-D4ELISA試劑盒豚鼠白三烯D4(LTD4)ELISA試劑盒規(guī)格：96T/48T
Humanai-Epstein-Barrvirusaibody，EBVELISAKit人抗EB病毒抗體(EBV)ELISA試劑盒規(guī)格：96T/48T
大鼠糖皮質(zhì)類固醇受體(GR)ELISA試劑盒 ，英文名： GR ELISA Kit
人抗增殖細(xì)胞核抗原抗體(PCNA)ELISA檢測試劑盒Humanproliferatingcellnuclearaigenaibody,PCNAELISAKit 96T/48T
裸鼠克拉拉細(xì)胞蛋白(CC16)免疫試劑盒 Nude Mouse Clara cell protein,CC16 ELISA kit
CLIAKitforPS-2(HumanPresenilin2)ELISAKit人早老素2規(guī)格：48T/96T
石蠟切片組織BCL2蛋白表達(dá)熒光顯微鏡檢測試劑盒10/20次
ELISAKitHCⅡ人肝素輔因子Ⅱ規(guī)格：48T/96T
四分子交聯(lián)體5抗體（四旋蛋白）規(guī)格 大鼠細(xì)胞因子信號(hào)轉(zhuǎn)導(dǎo)抑制因子2(SOCS2)ELISA試劑盒 ，英文名： SOCS2 ELISA Kit
Mouse epithelial neuophil activating peptide 78 (ENA-78/CXCL5) ELISA Kit 小鼠上皮中性粒細(xì)胞活化肽78(ENA-78/CXCL5)ELISA試劑盒
MouseCarboxyterminalpropeptideoftypeⅠprocollagen,PⅠCPELISAKit 小鼠Ⅰ型前膠原羧基端肽(PⅠCP)ELISA試劑盒 96T/48T 進(jìn)口分裝
HSV-IIgM單純Ⅰ型病毒IgM(捕獲法一步法)
細(xì)胞IRAK1激酶活性定量檢測試劑盒(A/B/C)20次
ELISAKitLTB4大鼠白三烯B4規(guī)格：48T/96T
|
|
|
|
|
