|
| 產(chǎn)地 | 進口、國產(chǎn) |
| 品牌 | 上海莼試 |
| 保存條件 | Store at -20 °C |
| 貨號 | CS11008 |
| 應(yīng)用范圍 | WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 |
| CAS編號 | |
| 抗體名 | Anti-RAB3GAP2 |
| 克隆性 | |
| 靶點 | 詳見說明書 |
| 適應(yīng)物種 | 詳見說明書 |
| 形態(tài) | 詳見說明書 |
| 宿主 | 詳見說明書 |
| 亞型 | IgG |
| 標識物 | 詳見說明書 |
| 濃度 | 1mg/1ml% |
| 免疫原 | KLH conjugated synthetic peptide derived from human RAB3GAP2 |
RAB3-GTP酶激活蛋白催化亞單位2抗體說明書 英文名稱 Anti-RAB3GAP2
中文名稱 RAB3-GTP酶激活蛋白催化亞單位2抗體說明書
別 名 DKFZp434D245; FLJ14579; KIAA0839; p150; Rab3 GAP p150; Rab3 GAP regulatory subunit; Rab3 GAP150; Rab3 GTPase activating protein 150 kDa subunit; Rab3 GTPase activating protein non catalytic subunit; RAB3 GTPase activating protein subunit 2 (non catalytic); RAB3 GTPase activating protein subunit 2; RAB3GAP150; RGAP iso; RP11 568G11.1; RBGPR_HUMAN.
產(chǎn)品屬性：
濃 度 1mg/1ml
規(guī) 格 0.2ml/200μg
抗體來源 Rabbit
克隆類型 polyclonal
交叉反應(yīng) Human, Mouse, Rat, Dog, Cow, Horse, Rabbit, Sheep
產(chǎn)品類型 一抗
研究領(lǐng)域 細胞生物 發(fā)育生物學(xué) 神經(jīng)生物學(xué) 信號轉(zhuǎn)導(dǎo) G蛋白信號
蛋白分子量 predicted molecular weight: 156kDa
性 狀 Lyophilized or Liquid
免 疫 原 KLH conjugated synthetic peptide derived from human RAB3GAP2
亞 型 IgG
純化方法 affinity purified by Protein A
儲 存 液 Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4
RAB3-GTP酶激活蛋白催化亞單位2抗體說明書 產(chǎn)品應(yīng)用 WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500
（石蠟切片需做抗原修復(fù)）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Important Note This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
產(chǎn)品介紹 ab 3 GAP p150 is a ubiquitously expressed protein that contains 1,393 amino acids and belongs to the Rab3-GAP regulatory subunit family. Defects in Rab 3 GAP p150 are the cause of Martsolf and Warburg Micro syndrome. Both syndromes are characterized by congenital cataracts, microphthalmia, postnatal microcephaly and developmental delay, and are inherited in an autosomal recessive manner. The Rab3 GTPase-activating complex is a heterodimer composed of RAB3GAP and Rab 3 GAP p150 that interacts with DMXL2. Existing as two alternatively spliced isoforms, the Rab 3 GAP p150 gene is conserved in chimpanzee, dog, cow, rat, chicken, zebrafish, fruit fly, mosquito, A.thaliana and rice. The Rab 3 GAP p150 gene contains 36 exons and maps to human chromosome 1q41.
Function : RAB3GAP2 is a regulatory subunit of a GTPase activating protein that has specificity for Rab3 subfamily (RAB3A, RAB3B, RAB3C and RAB3D). Rab3 proteins are involved in regulated exocytosis of neurotransmitters and hormones. Rab3 GTPase-activating complex specifically converts active Rab3-GTP to the inactive form Rab3-GDP. It is required for normal eye and brain development and may participate in neurodevelopmental processes such as proliferation, migration and differentiation before synapse formation, and non-synaptic vesicular release of neurotransmitters.
Subunit : The Rab3 GTPase-activating complex is a heterodimer composed of RAB3GAP and RAB3-GAP150. The Rab3 GTPase-activating complex interacts with DMXL2
Subcellular Location : Cytoplasm. Note=In neurons, it is enriched in the synaptic soluble fraction.
Tissue Specificity : Ubiquitous.
DISEASE : efects in RAB3GAP2 are the cause of Martsolf syndrome (MARTS) [MIM:212720]. Martsolf syndrome is characterized by congenital cataracts, mental retardation, and hypogonadism. Inheritance is autosomal recessive.
Defects in RAB3GAP2 are the cause of Warburg micro syndrome type 2 (WARBM2) [MIM:614225]. WARBM2 is a rare syndrome characterized by microcephaly, microphthalmia, microcornia, congenital cataracts, optic atrophy, cortical dysplasia, in particular corpus callosum hypoplasia, severe mental retardation, spastic diplegia, and hypogonadism.
Similarity : Belongs to the Rab3-GAP regulatory subunit family.
Database links : UniProtKB/Swiss-Prot: Q9H2M9.1
實驗流程：
全、新、優(yōu)、品、好四大特點：
RAB3-GTP酶激活蛋白催化亞單位2抗體說明書 全：公司提供上萬種產(chǎn)品，涵蓋了生物試劑，elisa試劑盒，標準品，培養(yǎng)基，原裝耗材，抗體、培養(yǎng)基、ATCC細胞等，基本上各種科研所需產(chǎn)品在我司都能找到。
新：產(chǎn)品更新速度較快，基本上每周都有新產(chǎn)品出現(xiàn)。
優(yōu)：產(chǎn)品質(zhì)量好，投訴比較少。
好：我公司具有優(yōu)質(zhì)的技術(shù)團隊，產(chǎn)品一旦售出，實驗過程中遇到困難可提供在線技術(shù)咨詢。使您使用產(chǎn)品時沒有任何的后顧之憂。
正在熱銷的相關(guān)產(chǎn)品：
P73 protein P73抑制基因抗原Multi-class antibodies規(guī)格： 0.5mg
Anti-Angiotensin I 緊張素I抗體Multi-class antibodies規(guī)格： 0.2ml
Rhesus antibody Rh phospho-APP/ABPP(Tyr757) 磷酸化APP(Tyr757)淀粉樣肽前體蛋白抗體 規(guī)格 0.1ml
Surfacant Protein A(100-200) 濃縮液 0.1ml 進口分裝
UBE2D2 英文名稱： 泛素蛋白連接酶D2抗體 0.2ml
DHRS9 英文名稱： 短鏈脫氫酶/還原酶家族9抗體 0.1ml
Anti-Angiotensin I 緊張素I抗體Multi-class antibodies規(guī)格： 0.2ml
Anti-PAK2 /FITC 熒光素標記p21激活激酶2抗體IgGMulti-class antibodies規(guī)格： 0.2ml
Goat Anti-rabbit IgG 羊抗兔IgG (親和層析純化)Multi-class antibodies規(guī)格： 1mg
抗g-氨基B1受體抗體 anti-GABAB1 0.2ml
Goat Anti-rabbit IgG/Alexa Fluor 555 Alexa Fluor 555標記的羊抗兔IgG 0.1ml
FLNB 英文名稱： 細絲蛋白3抗體 0.2ml
Rhesus antibody Rh Phospho-SRC-3 (Thr24) 磷酸化類固醇受體輔助活化因子-3 規(guī)格 0.1ml
Goat Anti-rabbit IgG 羊抗兔IgG (親和層析純化)Multi-class antibodies規(guī)格： 1mg
VEGF 內(nèi)皮生長因子(多肽抗原)Multi-class antibodies規(guī)格： 0.5mg
Anti-Caspase-6 (NT) 半胱胺酸蛋白酶蛋白-6抗體(N端)Multi-class antibodies規(guī)格： 0.1ml
Rhesus antibody Rh PCK2 磷酸羧化酶2抗體 規(guī)格 0.2ml
TIMP1 Kit Human 人 TIMP1 / EPA / CLGI ELISA配對抗體 ELISA
TACC1 英文名稱： 癌、抗原GA55抗體 0.2ml
C21orf88 英文名稱： 21號染色體開放閱讀框88抗體 0.2ml
Anti-Caspase-6 (NT) 半胱胺酸蛋白酶蛋白-6抗體(N端)Multi-class antibodies規(guī)格： 0.1ml
BGdium
LB Broth, Lennox incubation media LB Broth, Lennox
丁香假單胞菌 支/瓶
XyloseLysineDesoxycholateMedium
DRBCAgar
AcetamideAgar
假單胞F瓊脂 250(g) incubation media 假單胞F瓊脂 250(g)
波爾頓肉湯 Bolton Selective Enrichment Broth 250克 彎曲桿菌的選擇性增菌培養(yǎng)
HE瓊脂(HE)250用于沙門氏菌的選擇性分離培養(yǎng)(FDA標準)incubationmediaHE瓊脂(HE)250用于沙門氏菌的選擇性分離培養(yǎng)(FDA標準)
EF-18瓊脂 250g 用于濾膜法檢測食品中沙門氏菌(SN/T1059.1)
RAB3-GTP酶激活蛋白催化亞單位2抗體說明書 葡萄糖半固體培養(yǎng)基 250(g) incubation media 葡萄糖半固體培養(yǎng)基 250(g)
動力-吲哚-尿素培養(yǎng)基基礎(chǔ)(MIU) 250(g) incubation media 動力-吲哚-尿素培養(yǎng)基基礎(chǔ)(MIU) 250(g)
SIM培養(yǎng)基 250(g) incubation media SIM培養(yǎng)基 250(g)
乳糖肉湯(LB) 250(g) incubation media 乳糖肉湯(LB) 250(g)
技術(shù)外包服務(wù):
★RAB3-GTP酶激活蛋白催化亞單位2抗體說明書 分子生物學(xué)：質(zhì)粒抽提、PCR、Q-PCR、RT-PCR、分子生物學(xué)：基因合成、引物合成、基因測序、載體構(gòu)建等
★蛋白工程：原核、哺乳動物蛋白表達系統(tǒng)等
★病毒包裝：腺病毒、慢病毒等
★抗體工程：磁珠分選、病理染色、WB、ELISA、IP、IF、IHC、FACS、Confocal等等
★細胞工程：細胞表型分析(凋亡、增殖、周期、遷移、侵襲、修復(fù)、克隆形成)、細胞培養(yǎng)、細胞膜制備、穩(wěn)定細胞株構(gòu)建、細胞RNAi技術(shù)等等。
|
|
|
|
|
