|
| 產(chǎn)地 | 進(jìn)口、國產(chǎn) |
| 品牌 | 上海莼試 |
| 保存條件 | Store at -20 °C |
| 貨號 | CS10640 |
| 應(yīng)用范圍 | WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:50-200 |
| CAS編號 | |
| 抗體名 | Anti-Protein S/PROS |
| 克隆性 | |
| 靶點 | 詳見說明書 |
| 適應(yīng)物種 | 詳見說明書 |
| 形態(tài) | 詳見說明書 |
| 宿主 | 詳見說明書 |
| 亞型 | IgG |
| 標(biāo)識物 | 詳見說明書 |
| 濃度 | 1mg/1ml% |
| 免疫原 | KLH conjugated synthetic peptide derived from human Protein S/PROS |
技術(shù)外包服務(wù):
★蛋白S抗體說明書 分子生物學(xué)：質(zhì)粒抽提、PCR、Q-PCR、RT-PCR、分子生物學(xué)：基因合成、引物合成、基因測序、載體構(gòu)建等
★蛋白工程：原核、哺乳動物蛋白表達(dá)系統(tǒng)等
★病毒包裝：腺病毒、慢病毒等
★抗體工程：磁珠分選、病理染色、WB、ELISA、IP、IF、IHC、FACS、Confocal等等
★細(xì)胞工程：細(xì)胞表型分析(凋亡、增殖、周期、遷移、侵襲、修復(fù)、克隆形成)、細(xì)胞培養(yǎng)、細(xì)胞膜制備、穩(wěn)定細(xì)胞株構(gòu)建、細(xì)胞RNAi技術(shù)等等。
實驗流程：
蛋白S抗體說明書 英文名稱 Anti-Protein S/PROS
中文名稱 蛋白S抗體說明書
別 名 Preproprotein S; Propiece of latent protein S; PROS 1; PROS; PROS_HUMAN; PROS1; Protein S alpha; Protein Sa; PS 21; PS 22; PS 23; PS 24; PS 25; PS 26; PS21; PS22; PS23; PS24; PS25; PS26; PSA; Vitamin K dependent protein S; Vitamin K-dependent protein S.
產(chǎn)品屬性：
濃 度 1mg/1ml
規(guī) 格 0.2ml/200μg
抗體來源 Rabbit
克隆類型 polyclonal
交叉反應(yīng) Human, Mouse, Rat, Cow, Horse, Sheep
產(chǎn)品類型 一抗
研究領(lǐng)域 心 細(xì)胞生物 免疫學(xué)
蛋白分子量 predicted molecular weight: 71kDa
性 狀 Lyophilized or Liquid
免 疫 原 KLH conjugated synthetic peptide derived from human Protein S/PROS
亞 型 IgG
純化方法 affinity purified by Protein A
儲 存 液 Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4
蛋白S抗體說明書 產(chǎn)品應(yīng)用 WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:50-200
（石蠟切片需做抗原修復(fù)）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Important Note This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
產(chǎn)品介紹 Protein S (PROS) is a vitamin K-dependent plasma protein that inhibits blood clotting by serving as a cofactor for activated protein C (APC) and facilitates clearance of early apoptotic cells. In the plasma, circulating Protein S becomes inactive upon complexing with C4b-binding protein (C4BP); 60-70% of Protein S circulates in complex with C4BP. Calcium-dependent association of C4BP-Protein S with apoptotic cells influences the regulation of complement activation. Protein S has APC-independent anticoagulant activity through direct inhibition of prothrombin activation via interactions with Factor X A, Factor V A and phospholipids. Autosomal dominant Protein S deficiency (levels 15 to 37% of normal) correlates with severe recurrent venous thrombosis.
Function : Anticoagulant plasma protein; it is a cofactor to activated protein C in the degradation of coagulation factors Va and VIIIa. It helps to prevent coagulation and stimulating fibrinolysis.
Subcellular Location : Secreted
Tissue Specificity : Plasma.
DISEASE : Defects in PROS1 are the cause of thrombophilia due to protein S deficiency, autosomal dominant (THPH5) [MIM:612336]. A hemostatic disorder characterized by impaired regulation of blood coagulation and a tendency to recurrent venous thrombosis. However, many adults with heterozygous disease may be asymptomatic. Based on the plasma levels of total and free PROS1 antigen as well as the serine protease-activated protein C cofactor activity, three types of PROS1D have been described: type I, characterized by reduced total and free PROS1 antigen levels together with reduced anticoagulant activity; type III, in which only free PROS1 antigen and PROS1 activity levels are reduced; and the rare type II which is characterized by normal concentrations of both total and free PROS1 antigen, but low cofactor activity.
Defects in PROS1 are the cause of thrombophilia due to protein S deficiency, autosomal recessive (THPH6) [MIM:614514]. A very rare and severe hematologic disorder resulting in thrombosis and secondary hemorrhage usually beginning in early infancy. Some affected individuals develop neonatal purpura fulminans, multifocal thrombosis, or intracranial hemorrhage.
Similarity : Contains 4 EGF-like domains.
Contains 1 Gla (gamma-carboxy-glutamate) domain.
Contains 2 laminin G-like domains.
Database links : UniProtKB/Swiss-Prot: P07225.1
全、新、優(yōu)、品、好四大特點：
蛋白S抗體說明書 全：公司提供上萬種產(chǎn)品，涵蓋了生物試劑，elisa試劑盒，標(biāo)準(zhǔn)品，培養(yǎng)基，原裝耗材，抗體、培養(yǎng)基、ATCC細(xì)胞等，基本上各種科研所需產(chǎn)品在我司都能找到。
新：產(chǎn)品更新速度較快，基本上每周都有新產(chǎn)品出現(xiàn)。
優(yōu)：產(chǎn)品質(zhì)量好，投訴比較少。
好：我公司具有優(yōu)質(zhì)的技術(shù)團(tuán)隊，產(chǎn)品一旦售出，實驗過程中遇到困難可提供在線技術(shù)咨詢。使您使用產(chǎn)品時沒有任何的后顧之憂。
正在熱銷的相關(guān)產(chǎn)品：
Anti-NOS-3/eNOS /FITC 熒光素標(biāo)記合成酶-3抗體(內(nèi)皮型)IgGMulti-class antibodies規(guī)格： 0.2ml
Anti-ZNF474/FITC 熒光素標(biāo)記鋅指蛋白474抗體IgGMulti-class antibodies規(guī)格： 0.2ml
半胱胺酸蛋白酶蛋白-6抗體 Anti-Caspase-6 0.1ml
Goat Anti-Guinea pig IgG/APC APC標(biāo)記的羊抗豚鼠IgG 0.1ml
human Fibrinogen 英文名稱： 人纖維蛋白原單克隆抗體 0.1ml
Rhesus antibody Rh POLA2 DNA聚合酶α2抗體 規(guī)格 0.2ml
Anti-ZNF474/FITC 熒光素標(biāo)記鋅指蛋白474抗體IgGMulti-class antibodies規(guī)格： 0.2ml
MBP/MBL (Rat Mannma binding protein/mannan binding lectin,MBP/MBL) ELISA Kit Rat Mannma binding protein/mannan binding lectinMulti-class antibodies規(guī)格： 48T
Anti-phospho-STAT3 (Thr705) 磷酸化信號轉(zhuǎn)導(dǎo)和轉(zhuǎn)錄激活因子3抗體Multi-class antibodies規(guī)格： 0.1ml
Rhesus antibody Rh Goat Anti-human IgG/FITC FITC標(biāo)記的羊抗人IgG 規(guī)格 0.3ml
cGMP(Mouse Cyclic guanosine monophosphate) ELISA Kit 小鼠環(huán)磷酸鳥苷 96T
NADPH oxidase 4 英文名稱： NADPH氧化酶NOX家族的成員4抗體 0.2ml
phospho-Bid (Ser61) 英文名稱： 磷酸化BH3結(jié)構(gòu)域凋亡誘導(dǎo)蛋白抗體 0.1ml
Anti-phospho-STAT3 (Thr705) 磷酸化信號轉(zhuǎn)導(dǎo)和轉(zhuǎn)錄激活因子3抗體Multi-class antibodies規(guī)格： 0.1ml
PK(Human pyruvate kinase) ELISA Kit 人酸激酶Multi-class antibodies規(guī)格： 48T
Anti-NIK/MAPKKK14 NFkB誘導(dǎo)激酶抗體Multi-class antibodies規(guī)格： 0.2ml
Rhesus antibody Rh IL-16 白介素16抗體 規(guī)格 0.1ml
6-K-PG(Mouse 6-keto-prostaglandin) ELISA Kit 小鼠6酮素 96T
phospho-PAK6(Ser165) 英文名稱： 磷酸化P21蛋白激活的蛋白激酶6 0.1ml
CPT1A 英文名稱： 肉毒堿棕櫚?；D(zhuǎn)移酶1A抗體 0.1ml
Anti-NIK/MAPKKK14 NFkB誘導(dǎo)激酶抗體Multi-class antibodies規(guī)格： 0.2ml
CL-0244WISH(人羊膜細(xì)胞)5×106cells/瓶×2
SRGN Others Human 人 Serglycin / SRGN 人細(xì)胞裂解液 (陽性對照)
人骨骼肌細(xì)胞cDNAHSkMC cDNA
4T1細(xì)胞，人癌細(xì)胞 昆蟲細(xì)胞系,Sf-21細(xì)胞 肺微內(nèi)皮細(xì)胞Many types of cells包裝：5 × 105次方(1ml)
Y3-Ag 1.2.3(大鼠細(xì)胞) 5×106cells/瓶×2
NHDF adult Pellet 正常人皮膚成纖維細(xì)胞團(tuán)塊(捐獻(xiàn)者) > 1 mio.cells CCCSCK
CL-0242Vero(非洲綠猴腎細(xì)胞)5×106cells/瓶×2
IL17RB Others Human 人 IL17BR / IL17RB / IL-17 Receptor B 人細(xì)胞裂解液 (陽性對照)
人平滑肌細(xì)胞cDNAHBSMC cDNA
小型豬腎細(xì)胞;MPK 畸胎癌細(xì)胞，P19細(xì)胞 W256細(xì)胞，Walker氏癌256瘤株
Sars結(jié)構(gòu)蛋白表達(dá)株;293 001A
HA Others H5N3 甲型 H5N3 (A/duck/Hokkaido/167/2007) 血凝素 (Hemagglutinin / HA) 人細(xì)胞裂解液 (陽性對照)
蛋白S抗體說明書 CD63 Others Rat 大鼠 CD63 / Tspan-30 / Teaspanin-30 人細(xì)胞裂解液 (陽性對照)
CL-0316A7r5(大鼠胸大動脈平滑肌細(xì)胞)5×106cells/瓶×2
人海馬趾星形膠質(zhì)細(xì)胞總RNAHA-h NA
盤羊皮膚細(xì)胞;ASHS3 卵巢細(xì)胞，Lec1細(xì)胞 L7712細(xì)胞，615小鼠T細(xì)胞性瘤株
SV40T轉(zhuǎn)化的人胚腎細(xì)胞;293T
HA Others H5N1 甲型 H5N1 (A/Egypt/N05056/2009) 血凝素 (Hemagglutinin / HA) 人細(xì)胞裂解液 (陽性對照)
|
|
|
|
|
