|
| 產(chǎn)地 | 進口、國產(chǎn) |
| 品牌 | 上海莼試 |
| 保存條件 | Store at -20 °C |
| 貨號 | CS10540 |
| 應(yīng)用范圍 | WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 |
| CAS編號 | |
| 抗體名 | Anti-P2RX7 |
| 克隆性 | |
| 靶點 | 詳見說明書 |
| 適應(yīng)物種 | 詳見說明書 |
| 形態(tài) | 詳見說明書 |
| 宿主 | 詳見說明書 |
| 亞型 | IgG |
| 標(biāo)識物 | 詳見說明書 |
| 濃度 | 1mg/1ml% |
| 免疫原 | KLH conjugated synthetic peptide derived from human P2RX7 (115-160aa) |
嘌呤受體P2X7抗體說明書 英文名稱 Anti-P2RX7
中文名稱 嘌呤受體P2X7抗體說明書
別 名 ATP receptor; P2X purinoceptor 7; P2X7; P2Z receptor; Purinergic receptor; purinergic receptor P2X, ligand gated ion channel 7; P2RX7_HUMAN.
產(chǎn)品屬性：
濃 度 1mg/1ml
規(guī) 格 0.2ml/200μg
抗體來源 Rabbit
克隆類型 polyclonal
交叉反應(yīng) Human, Mouse, Rat, Dog, Pig, Horse, Rabbit
產(chǎn)品類型 一抗
研究領(lǐng)域 神經(jīng)生物學(xué) 通道蛋白 細胞膜受體
蛋白分子量 predicted molecular weight: 69kDa
性 狀 Lyophilized or Liquid
免 疫 原 KLH conjugated synthetic peptide derived from human P2RX7 (115-160aa)
亞 型 IgG
純化方法 affinity purified by Protein A
儲 存 液 Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4
嘌呤受體P2X7抗體說明書 產(chǎn)品應(yīng)用 WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500
（石蠟切片需做抗原修復(fù)）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Important Note This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
產(chǎn)品介紹 The P2X receptor family is comprised of ligand-gated ion channels that allow for the increased permeability of calcium into the cell in response to extracellular ATP. The seven P2X receptors, P2X1-P2X7, form either homomeric or heteromeric channels or both. They are characterized by intracellular amino- and carboxy-termini. P2X receptors are expressed in a wide variety of tissues, including neurons, prostate, bladder, pancreas, colon, testis and ovary. The major function of the P2X receptors is to mediate synaptic transmissions between neurons and to other tissues via the binding of extracellular ATP, which acts as a neurotransmitter. The P2X receptors may be involved in the onset of necrosis or apoptosis after prolonged exposure to high concentrations of extracellular ATP.
Function : The product P2RX7 belongs to the family of purinoceptors for ATP. This receptor functions as a ligand-gated ion channel and is responsible for ATP-dependent lysis of macrophages through the formation of membrane pores permeable to large molecules. Activation of this nuclear receptor by ATP in the cytoplasm may be a mechanism by which cellular activity can be coupled to changes in gene expression.
Subunit : Functional P2XRs are organized as homomeric and heteromeric trimers. Interacts with LAMA3, ITGB2, ACTB, ACTN4, SVIL, MPP3, HSPA1, HSPCB, HSPA8, PIK230 and PTPRB.
Subcellular Location : Cell membrane; Multi-pass membrane protein.
ADP-ribosylation at Arg-125 is necessary and sufficient to activate P2RX7 and gate the channel (By similarity).
Palmitoylation of several cysteines in the C-terminal cytoplasmic tail is required for efficient localization to cell surface.
Similarity : Belongs to the P2X receptor family.
Database links : UniProtKB/Swiss-Prot: Q99572.4
實驗流程：
全、新、優(yōu)、品、好四大特點：
嘌呤受體P2X7抗體說明書 全：公司提供上萬種產(chǎn)品，涵蓋了生物試劑，elisa試劑盒，標(biāo)準(zhǔn)品，培養(yǎng)基，原裝耗材，抗體、培養(yǎng)基、ATCC細胞等，基本上各種科研所需產(chǎn)品在我司都能找到。
新：產(chǎn)品更新速度較快，基本上每周都有新產(chǎn)品出現(xiàn)。
優(yōu)：產(chǎn)品質(zhì)量好，投訴比較少。
好：我公司具有優(yōu)質(zhì)的技術(shù)團隊，產(chǎn)品一旦售出，實驗過程中遇到困難可提供在線技術(shù)咨詢。使您使用產(chǎn)品時沒有任何的后顧之憂。
正在熱銷的相關(guān)產(chǎn)品：
Anti-DC-SIGN/CD209/CLEC4L/FITC 熒光素標(biāo)記CD209抗體IgGMulti-class antibodies規(guī)格： 0.2ml
Anti-Phospho-PKM2 (Tyr105) /FITC 熒光素標(biāo)記磷酸化酸激酶M2抗體IgGMulti-class antibodies規(guī)格： 0.2ml
Rhesus antibody Rh CaMK2 beta/CaMK2 gamma 鈣/鈣調(diào)素依賴蛋白激酶2b/2γ抗體 規(guī)格 0.1ml
Cyclin D3(C-term) 周期素D3抗原 0.5mg
Hoxb3 英文名稱： 同源盒蛋白HoxB3抗體 0.2ml
Rhesus antibody Rh SEZ6L 樣相關(guān)蛋白6抗體 規(guī)格 0.2ml
Anti-Phospho-PKM2 (Tyr105) /FITC 熒光素標(biāo)記磷酸化酸激酶M2抗體IgGMulti-class antibodies規(guī)格： 0.2ml
Anti-Phospho-HSL (Ser552)/FITC 熒光素標(biāo)記磷酸化荷爾蒙敏感脂肪酶抗體IgGMulti-class antibodies規(guī)格： 0.2ml
Anti-PI3K/P85 alpha/FITC 熒光素標(biāo)記磷脂酰肌醇激酶抗體IgGMulti-class antibodies規(guī)格： 0.2ml
Rhesus antibody Rh ASP/AKAP associated Sperm Protein 相關(guān)蛋白AKAP抗體 規(guī)格 0.2ml
Donkey Anti-Guinea pig IgG/PE-CY5 PE-CY5標(biāo)記的驢抗豚鼠IgG 0.1ml
Glucose Oxidase 英文名稱： 葡萄糖氧化酶抗體 0.2ml
Rhesus antibody Rh Rabbit Anti-mouse IgG/PE-Cy3 PE-Cy3標(biāo)記的兔抗小鼠IgG 規(guī)格 0.1ml
Anti-PI3K/P85 alpha/FITC 熒光素標(biāo)記磷脂酰肌醇激酶抗體IgGMulti-class antibodies規(guī)格： 0.2ml
NA(Human neuraminidase) ELISA Kit 人神經(jīng)氨酸酶Multi-class antibodies規(guī)格： 48T
Anti-NEDD4L/NEDD4-2 泛素連接酶NEDD4-2抗體Multi-class antibodies規(guī)格： 0.2ml
Rhesus antibody Rh IL-6 白介素6 規(guī)格 0.1ml
MMP-3 ELISA kit 大鼠基質(zhì)金屬蛋白酶3 96T
phospho-PRKCZ(Thr500) 英文名稱： 磷酸化蛋白激酶C(T500)抗體 0.2ml
C8orf55 英文名稱： 8號染色體開放閱讀框55抗體 0.2ml
Anti-NEDD4L/NEDD4-2 泛素連接酶NEDD4-2抗體Multi-class antibodies規(guī)格： 0.2ml
CL-0432RTE(大鼠氣管上皮細胞)5×106cells/瓶×2
IL23 Others Mouse 小鼠 IL-23 / IL23A & IL12B Heterodimer 人細胞裂解液 (陽性對照)
人腸微內(nèi)皮細胞RNAHIMEC miRNA5 μg
RBE細胞，人細胞 小鼠艾氏腹水瘤細胞,ECA細胞 人羊膜上皮細胞
M14(人細胞) 5×106cells/瓶×2
NHEK.f pooled Pellet 正常人表皮角質(zhì)細胞團塊(少年者，混合來源) > 1 mio.cells 內(nèi)皮細胞培養(yǎng)基ECM
CL-0430RS1(大鼠皮膚成纖維樣細胞)5×106cells/瓶×2
IL22RA1 Others Canine 狗 IL22RA1 / IL22R 人細胞裂解液 (陽性對照)
人食道上皮細胞RNAHEEpiC miRNA5 μg
兔間變表皮鱗株;VX2 細胞，22RV1細胞 MDCK superdome細胞，狗腎細胞隆突型
人永生化淋巴細胞;CNLMG-B5537LC
HA Others H3N2 甲型 H3N2 (A/Aichi/2/1968) 血凝素HA1 (Hemagglutinin) 人細胞裂解液 (陽性對照)
嘌呤受體P2X7抗體說明書 HAVCR2 Others Mouse 小鼠 TIM3 / HAVCR2 人細胞裂解液 (陽性對照)
小鼠紋狀體神經(jīng)元MN-s
人胚;MRC-5
DMS153細胞，人小細胞細胞 大鼠腎上腺嗜鉻細胞瘤細胞,PC12細胞 CM-H127人晶狀體上皮細胞完全培養(yǎng)基100mL
PANC-1(人*癌細胞) 5×106cells/瓶×2
Promocell C-28020 Hematopoietic ProgenitorMedium, 造血祖細胞培養(yǎng)基(即用型) 100ml
技術(shù)外包服務(wù):
★嘌呤受體P2X7抗體說明書 分子生物學(xué)：質(zhì)粒抽提、PCR、Q-PCR、RT-PCR、分子生物學(xué)：基因合成、引物合成、基因測序、載體構(gòu)建等
★蛋白工程：原核、哺乳動物蛋白表達系統(tǒng)等
★病毒包裝：腺病毒、慢病毒等
★抗體工程：磁珠分選、病理染色、WB、ELISA、IP、IF、IHC、FACS、Confocal等等
★細胞工程：細胞表型分析(凋亡、增殖、周期、遷移、侵襲、修復(fù)、克隆形成)、細胞培養(yǎng)、細胞膜制備、穩(wěn)定細胞株構(gòu)建、細胞RNAi技術(shù)等等。
|
|
|
|
|
