|
| 產(chǎn)地 | 進(jìn)口、國(guó)產(chǎn) |
| 品牌 | 上海莼試 |
| 保存條件 | Store at -20 °C |
| 貨號(hào) | CS10304 |
| 應(yīng)用范圍 | WB=1:100-500 ELISA=1:500-1000 IP=1:20-100 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 |
| CAS編號(hào) | |
| 抗體名 | Anti-PNPLA6/NTE |
| 克隆性 | |
| 靶點(diǎn) | 詳見說(shuō)明書 |
| 適應(yīng)物種 | 詳見說(shuō)明書 |
| 形態(tài) | 詳見說(shuō)明書 |
| 宿主 | 詳見說(shuō)明書 |
| 亞型 | IgG |
| 標(biāo)識(shí)物 | 詳見說(shuō)明書 |
| 濃度 | 1mg/1ml% |
| 免疫原 | KLH conjugated synthetic peptide derived from human PNPLA6 |
技術(shù)外包服務(wù):
★含patatin樣磷脂酶6抗體說(shuō)明書 分子生物學(xué)：質(zhì)粒抽提、PCR、Q-PCR、RT-PCR、分子生物學(xué)：基因合成、引物合成、基因測(cè)序、載體構(gòu)建等
★蛋白工程：原核、哺乳動(dòng)物蛋白表達(dá)系統(tǒng)等
★病毒包裝：腺病毒、慢病毒等
★抗體工程：磁珠分選、病理染色、WB、ELISA、IP、IF、IHC、FACS、Confocal等等
★細(xì)胞工程：細(xì)胞表型分析(凋亡、增殖、周期、遷移、侵襲、修復(fù)、克隆形成)、細(xì)胞培養(yǎng)、細(xì)胞膜制備、穩(wěn)定細(xì)胞株構(gòu)建、細(xì)胞RNAi技術(shù)等等。
實(shí)驗(yàn)流程：
含patatin樣磷脂酶6抗體說(shuō)明書 英文名稱 Anti-PNPLA6/NTE
中文名稱 含patatin樣磷脂酶6抗體說(shuō)明書
別 名 Neuropathy target esterase; NTEMND; Patatin like phospholipase domain containing 6; Patatin like phospholipase domain containing protein 6; Patatin-like phospholipase domain-containing protein 6; PLPL6_HUMAN; Pnpla6; SPG39; sws.
產(chǎn)品屬性：
濃 度 1mg/1ml
規(guī) 格 0.1ml/100μg 0.2ml/200μg
抗體來(lái)源 Rabbit
克隆類型 polyclonal
交叉反應(yīng) Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse
產(chǎn)品類型 一抗
研究領(lǐng)域 細(xì)胞生物 神經(jīng)生物學(xué) 信號(hào)轉(zhuǎn)導(dǎo) 激酶和磷酸酶
蛋白分子量 predicted molecular weight: 150kDa
性 狀 Lyophilized or Liquid
免 疫 原 KLH conjugated synthetic peptide derived from human PNPLA6
亞 型 IgG
純化方法 affinity purified by Protein A
儲(chǔ) 存 液 Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4
含patatin樣磷脂酶6抗體說(shuō)明書 產(chǎn)品應(yīng)用 WB=1:100-500 ELISA=1:500-1000 IP=1:20-100 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500
（石蠟切片需做抗原修復(fù)）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Important Note This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
產(chǎn)品介紹 Phospholipase B that deacylates intracellular phosphatidylcholine (PtdCho), generating glycerophosphocholine (GroPtdCho). This deacylation occurs at both sn-2 and sn-1 positions of PtdCho. Its specific chemical modification by certain organophosphorus (OP) compounds leads to distal axonopathy.
Tissue specificity;Expressed in brain, placenta, kidney, neuron and skeletal muscle.
Involvement in diseaseDefects in PNPLA6 are the cause of spastic paraplegia autosomal recessive type 39 (SPG39) ; also known as NTE-related motor neuron disorder (NTEMND). Spastic paraplegia is a neurodegenerative disorder characterized by a slow, gradual, progressive weakness and spasticity of the lower limbs. Rate of progression and the severity of symptoms are quite variable. Initial symptoms may include difficulty with balance, weakness and stiffness in the legs, muscle spasms, and dragging the toes when walking. In some forms of the disorder, bladder symptoms (such as incontinence) may appear, or the weakness and stiffness may spread to other parts of the body. SPG39 is associated with a motor axonopathy affecting upper and lower limbs and resulting in progressive wasting of distal upper and lower extremity muscles.
Function : Phospholipase B that deacylates intracellular phosphatidylcholine (PtdCho), generating glycerophosphocholine (GroPtdCho). This deacylation occurs at both sn-2 and sn-1 organophosphorus (OP) compounds leads to distal axonopathy.
Tissue Specificity : Expressed in brain, placenta, kidney, neuron and skeletal muscle.
Post-translational modifications : Glycosylated.
DISEASE : Defects in PNPLA6 are the cause of spastic paraplegia autosomal recessive type 39 (SPG39) [MIM:612020]; also known as NTE-related motor neuron disorder (NTEMND). Spastic paraplegia is a neurodegenerative disorder characterized by a slow, gradual, progressive weakness and spasticity of the lower limbs. Rate of progression and the severity of symptoms are quite variable. Initial symptoms may include difficulty with balance, weakness and stiffness in the legs, muscle spasms, and dragging the toes when walking. In some forms of the disorder, bladder symptoms (such as incontinence) may appear, or the weakness and stiffness may spread to other parts of the body. SPG39 is associated with a motor axonopathy affecting upper and lower limbs and resulting in progressive wasting of distal upper and lower extremity muscles.
Similarity : Belongs to the NTE family.
Contains 3 cyclic nucleotide-binding domains.
Contains 1 patatin domain.
全、新、優(yōu)、品、好四大特點(diǎn)：
含patatin樣磷脂酶6抗體說(shuō)明書 全：公司提供上萬(wàn)種產(chǎn)品，涵蓋了生物試劑，elisa試劑盒，標(biāo)準(zhǔn)品，培養(yǎng)基，原裝耗材，抗體、培養(yǎng)基、ATCC細(xì)胞等，基本上各種科研所需產(chǎn)品在我司都能找到。
新：產(chǎn)品更新速度較快，基本上每周都有新產(chǎn)品出現(xiàn)。
優(yōu)：產(chǎn)品質(zhì)量好，投訴比較少。
好：我公司具有優(yōu)質(zhì)的技術(shù)團(tuán)隊(duì)，產(chǎn)品一旦售出，實(shí)驗(yàn)過(guò)程中遇到困難可提供在線技術(shù)咨詢。使您使用產(chǎn)品時(shí)沒(méi)有任何的后顧之憂。
正在熱銷的相關(guān)產(chǎn)品：
BAFF-R(Human B cell activation factorr from the tumor necrosis factor family receptor) ELISA Kit 人B細(xì)胞活化因子受體Multi-class antibodies規(guī)格： 48T
Anti-GFP 綠色熒光蛋白抗體Multi-class antibodies規(guī)格： 0.2ml
Rhesus antibody Rh Mouse Anti-Guinea pig IgG/AP 堿性磷酸酶(AP)標(biāo)記的小鼠抗豚鼠IgG 規(guī)格 0.1ml
HSP-40(Human Heat Shock Protein 40) ELISA Kit 人熱休克蛋白40 96T
RGAG4 英文名稱： RGAG4蛋白抗體 0.2ml
Phospho-CHK2 (ser33) 英文名稱： 磷酸化細(xì)胞周期檢測(cè)點(diǎn)激酶2抗體 0.1ml
Anti-GFP 綠色熒光蛋白抗體Multi-class antibodies規(guī)格： 0.2ml
adiponectin(humen) 人脂聯(lián)素Multi-class antibodies規(guī)格： 48T
Anti-CK20 細(xì)胞角蛋白20抗體Multi-class antibodies規(guī)格： 0.2ml
Rhesus antibody Rh NRP1/CD304 神經(jīng)纖毛蛋白1抗體 規(guī)格 0.1ml
processing solution 顯影液試劑 200ml
TRF2 英文名稱： 端粒結(jié)合蛋白2抗體 0.1ml
C7orf10 英文名稱： 7號(hào)染色體開放閱讀框10抗體 0.2ml
Anti-CK20 細(xì)胞角蛋白20抗體Multi-class antibodies規(guī)格： 0.2ml
Anti-Phospho-MYL2 (Ser19) /FITC 熒光素標(biāo)記磷酸化肌球蛋白輕鏈2抗體IgGMulti-class antibodies規(guī)格： 0.2ml
Anti-TrK A/FITC 熒光素標(biāo)記酪氨酸激酶A抗體IgGMulti-class antibodies規(guī)格： 0.2ml
Rhesus antibody Rh ABCB6 ATP結(jié)合蛋白家族6抗體 規(guī)格 0.1ml
Mouse Anti-Guinea pig IgG/Alexa Fluor 488 Alexa Fluor 488標(biāo)記的小鼠抗豚鼠IgG 0.1ml
GLRA4 英文名稱： 甘酸受體α4抗體 0.2ml
Rhesus antibody Rh Rab24 ras基因相關(guān)蛋白R(shí)ab24抗體 規(guī)格 0.2ml
Anti-TrK A/FITC 熒光素標(biāo)記酪氨酸激酶A抗體IgGMulti-class antibodies規(guī)格： 0.2ml
大鼠可溶性Toll樣受體2(sTLR2)ELISA試劑盒 ，英文名： sTLR2 ELISA Kit
人胎盤生長(zhǎng)因子(PLGF)ELISA檢測(cè)試劑盒Humanplaceagrowthfactor,PLGFELISAkit 96T/48T
Zeranol(玉米赤霉醇)免疫試劑盒 Zeranol ELISA Kit
CLIAKitforOJ/IleRS(Humanai-OJ-aibody)ELISAKit人OJ抗體/抗異亮氨酰NA合成酶抗體規(guī)格：48T/96T
特定微型RNA目標(biāo)基因探測(cè)技術(shù)服務(wù)1個(gè)分子
ELISAKitβ-OHB人β規(guī)格：48T/96T
大鼠白介素8受體α(IL8Rα)ELISA試劑盒 ，英文名： IL8Rα ELISA Kit
Human beta 2 iegrin (iegrin beta 2/CD11+CD18) ELISA kit E 人β2整合素(iegrin β2/CD11+CD18)ELISA試劑盒E
PlaVitaminB6,VB6ELISAKit 植物維生素B6(VB6)ELISA試劑盒 96T/48T 進(jìn)口分裝
CLIAKitforCF(HumanCiliaryNeuroophicFactor)ELISAKit人睫狀神經(jīng)營(yíng)養(yǎng)因子規(guī)格：48T/96T
細(xì)胞游離膽固醇毛地黃皂苷法(DIGITONIN)舒爾茨染色試劑盒50次
RatCaveolin-1,Cav-1ELISAKit大鼠窖蛋白Caveolin1(Cav-1)ELISA試劑盒規(guī)格：96T/48T
含patatin樣磷脂酶6抗體說(shuō)明書 大鼠促腎上腺皮質(zhì)激素受體(ACTHR)ELISA試劑盒 ，英文名： ACTHR ELISA Kit
Human S100B protein (S-100B) ELISA Kit 人S100B蛋白(S-100B)ELISA試劑盒
RatSolubleIercellularAdhesionMolecule1,sICAM-1ELISAKit 大鼠可溶性細(xì)胞間粘附分子1(sICAM-1)ELISA試劑盒 96T/48T 進(jìn)口分裝
CLIAKitforCT(MouseCalcitonin)ELISAKit小鼠降鈣素規(guī)格：48T/96T
細(xì)胞微管分離試劑盒10次
RatEndocrineglandvascularendothelialgrowthfactor,EG-VEGFELISAKit大鼠腺來(lái)源的內(nèi)皮生長(zhǎng)因子(EG-VEGF)ELISA試劑盒規(guī)格：96T/48T
|
|
|
|
|
