![]() |
產(chǎn)地 | 進(jìn)口、國產(chǎn) |
品牌 | 上海莼試 |
保存條件 | Store at -20 °C |
貨號 | CS9845 |
應(yīng)用范圍 | WB=1:100-500 ELISA=1:500-1000 IP=1:20-100 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 |
CAS編號 | |
抗體名 | Anti-Neurobeachin |
克隆性 | |
靶點(diǎn) | 詳見說明書 |
適應(yīng)物種 | 詳見說明書 |
形態(tài) | 詳見說明書 |
宿主 | 詳見說明書 |
亞型 | IgG |
標(biāo)識物 | 詳見說明書 |
濃度 | 1mg/1ml% |
免疫原 | KLH conjugated synthetic peptide derived from Fruit fly Neurobeachin N-terminus |
全、新、優(yōu)、品、好四大特點(diǎn):
蛋白激酶錨定蛋白抗體費(fèi)用 全:公司提供上萬種產(chǎn)品,涵蓋了生物試劑,elisa試劑盒,標(biāo)準(zhǔn)品,培養(yǎng)基,原裝耗材,抗體、培養(yǎng)基、ATCC細(xì)胞等,基本上各種科研所需產(chǎn)品在我司都能找到。
新:產(chǎn)品更新速度較快,基本上每周都有新產(chǎn)品出現(xiàn)。
優(yōu):產(chǎn)品質(zhì)量好,投訴比較少。
好:我公司具有優(yōu)質(zhì)的技術(shù)團(tuán)隊(duì),產(chǎn)品一旦售出,實(shí)驗(yàn)過程中遇到困難可提供在線技術(shù)咨詢。使您使用產(chǎn)品時(shí)沒有任何的后顧之憂。
蛋白激酶錨定蛋白抗體費(fèi)用 英文名稱 Anti-Neurobeachin
中文名稱 蛋白激酶錨定蛋白抗體費(fèi)用
別 名 A-kinase anchor protein 550; d AKAP 550; Neurobeachin protein; Rugose protein; AKAP550; NBEA_DROME.
產(chǎn)品屬性:
濃 度 1mg/1ml
規(guī) 格 0.2ml/200μg
抗體來源 Rabbit
克隆類型 polyclonal
交叉反應(yīng) Fruit Fly
產(chǎn)品類型 一抗
研究領(lǐng)域 細(xì)胞生物
蛋白分子量 predicted molecular weight: 395kDa
性 狀 Lyophilized or Liquid
免 疫 原 KLH conjugated synthetic peptide derived from Fruit fly Neurobeachin N-terminus
亞 型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M PBS, pH 7.4 with 10 mg/ml BSA and 0.1% Sodium azide
蛋白激酶錨定蛋白抗體費(fèi)用 產(chǎn)品應(yīng)用 WB=1:100-500 ELISA=1:500-1000 IP=1:20-100 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500
(石蠟切片需做抗原修復(fù))
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Important Note This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
產(chǎn)品介紹 Neurobeachin binds to type II regulatory subunits of protein kinase A and anchors/targets them to the membrane. It may anchor the kinase to cytoskeletal and/or organelle-associated proteins. Neurobeachin, is also a neuron-specific multidomain protein of 327 kDa with a high-affinity binding site for the type II regulatory subunit of protein kinase A. Neurobeachin is peripherally associated with pleomorphic tubulovesicular endomembranes near the trans sides of Golgi stacks and throughout the cell body and cell processes. It is also found in a subpopulation of synapses, where it is concentrated at the postsynaptic plasma membrane.
Function : Binds to type II regulatory subunits of protein kinase A and anchors/targets them to the membrane. May anchor the kinase to cytoskeletal and/or organelle-associated proteins. Required for correct retinal pattern formation and may function in cell fate determination through its interactions with the EGFR and Notch signaling pathways.Subunit : Interacts with RII subunit of PKA and components of the EGFR-mediated and Notch-mediated signaling pathways.Subcellular Location : Cytoplasm. Membrane; Peripheral membrane protein.Tissue Specificity : In early embryos, ubiquitous expression with elevated levels in ventral furrow and flanking mesectodermal cells, neuroblasts and mesoderm. Late embryos show reduced expression in epidermis and skeletal muscle and elevated in nervous system, gut endothelium, tracheal system and salivary gland. Larvae show expression in imaginal disks and many neural cells. Developing eye imaginal disk shows expression throughout the disk and in the region of the morphogenetic furrow. Ubiquitous expression in adults with higher levels in head region.Similarity : Belongs to the WD repeat neurobeachin family.Contains 1 BEACH domain.Contains 5 WD repeats.Database links : UniProtKB/Swiss-Prot: Q9W4E2.3AKAP位于心肌細(xì)胞膜漿面L型Ca2+通道旁邊,通過錨定PKA,使其能迅速磷酸化Ca2+通道。有實(shí)驗(yàn)證明:當(dāng)阻斷PKA與AKMP的結(jié)合時(shí),PKA對Ca2+通道的磷酸化作用就被阻斷,說明AKMP錨定作用的關(guān)鍵性。
實(shí)驗(yàn)流程:
正在熱銷的相關(guān)產(chǎn)品:
Anti-CK19/Gold 膠體金離子標(biāo)記細(xì)胞角蛋白19抗體IgGMulti-class antibodies規(guī)格: 0.2ml
Anti-IRAK4/FITC 熒光素標(biāo)記白介素-1受體相關(guān)激酶4抗體IgGMulti-class antibodies規(guī)格: 0.2ml
Rhesus antibody Rh CCL24 嗜酸粒細(xì)胞趨化蛋白24抗體 規(guī)格 0.2ml
IL-16(Interleukin-16) 白介素16抗原 0.5mg
HPV16 E7 英文名稱: 人瘤病毒16型E7抗體 0.1ml
Rhesus antibody Rh SPAG8 相關(guān)抗原8抗體 規(guī)格 0.2ml
Anti-IRAK4/FITC 熒光素標(biāo)記白介素-1受體相關(guān)激酶4抗體IgGMulti-class antibodies規(guī)格: 0.2ml
vaspin(Mouse Visceral adipose-specific serine protease inhibitor) ELISA Kit 小鼠內(nèi)臟脂肪特異性絲氨酸蛋白酶抑制劑Multi-class antibodies規(guī)格: 48T
Anti-cath-G/CG /FITC 熒光素標(biāo)記組織蛋白酶G抗體IgGMulti-class antibodies規(guī)格: 0.2ml
Rhesus antibody Rh eIF3A 真核翻譯起始因子3A抗體 規(guī)格 0.1ml
Nasoniavitripennis vitellogenin,Vtg ELISA Kit 蝶蛹金小蜂卵黃蛋白原 96T
MKLP1 英文名稱: 有絲分裂驅(qū)動蛋白樣1抗體 0.2ml
Phospho-Ack1 (Tyr284) 英文名稱: 磷酸化Ack1抗體 0.1ml
Anti-cath-G/CG /FITC 熒光素標(biāo)記組織蛋白酶G抗體IgGMulti-class antibodies規(guī)格: 0.2ml
Anti-GSK-3 Beta /FITC 熒光素標(biāo)記糖原合酶激酶-3β抗體IgGMulti-class antibodies規(guī)格: 0.2ml
Anti-PACAP-27/38 /FITC 熒光素標(biāo)記腺苷酸環(huán)化酶激活肽-27/38抗體IgGMulti-class antibodies規(guī)格: 0.2ml
Rhesus antibody Rh BCMA/CD269 B淋巴細(xì)胞成熟因子抗體 規(guī)格 0.1ml
AHA3 peptide 植物蛋白AHA3抗原(擬南芥) 0.5mg
GLP-1 英文名稱: 胰素樣肽-1抗體 0.1ml
Rhesus antibody Rh Ractopamine /PAYLEAN (1B12) 小鼠抗萊克多巴胺單克隆抗體 規(guī)格 0.2ml
Anti-PACAP-27/38 /FITC 熒光素標(biāo)記腺苷酸環(huán)化酶激活肽-27/38抗體IgGMulti-class antibodies規(guī)格: 0.2ml
精酸雙水解酶試驗(yàn)用培養(yǎng)基(AD)5g生化培養(yǎng)基,用于弧菌的精酸試驗(yàn)
EthylVioletAziodeBroth
含鐵牛奶培養(yǎng)基 250 用于產(chǎn)氣莢膜梭菌的牛奶發(fā)酵試驗(yàn)
亞利桑那菌瓊脂(SA)250g/瓶用于亞利桑那菌的分離incubationmedia亞利桑那菌瓊脂(SA)250g/瓶用于亞利桑那菌的分離
TCBS瓊脂平板(9cm) 10個/包 用于致病性弧菌的選擇性分離
培養(yǎng)基R250g用于大腸菌群選擇性增菌
亮綠酚紅乳糖瓊脂 incubation media 亮綠酚紅乳糖瓊脂
L-酪氨酸營養(yǎng)瓊脂配套試劑 10支/盒 L-酪氨酸營養(yǎng)瓊脂基礎(chǔ)配套試劑
麥康凱瓊脂2號MaconkeyAgarNo.2用于腸道致病菌的選擇性分離、培養(yǎng)(OXOID方法)
LitmusMilkMedium
蛋白激酶錨定蛋白抗體費(fèi)用 3%NaCl葡萄糖(產(chǎn)氣)生化鑒定管 規(guī)格: 20支/盒 用途: 用于鑒別耐的弧菌利用糖源的能力。(鑒定副溶血性弧菌)
3%NaCl甘露醇生化鑒定管 規(guī)格: 20支/盒 用途: 用于弧菌的耐鹽試驗(yàn)。
3%NaCl蔗糖生化鑒定管 規(guī)格: 20支/盒 用途: 用于弧菌的耐鹽試驗(yàn)。
3%NaCl乳糖生化鑒定管 規(guī)格: 20支/盒 用途: 用于弧菌的耐鹽試驗(yàn)。
技術(shù)外包服務(wù):
★蛋白激酶錨定蛋白抗體費(fèi)用 分子生物學(xué):質(zhì)粒抽提、PCR、Q-PCR、RT-PCR、分子生物學(xué):基因合成、引物合成、基因測序、載體構(gòu)建等
★蛋白工程:原核、哺乳動物蛋白表達(dá)系統(tǒng)等
★病毒包裝:腺病毒、慢病毒等
★抗體工程:磁珠分選、病理染色、WB、ELISA、IP、IF、IHC、FACS、Confocal等等
★細(xì)胞工程:細(xì)胞表型分析(凋亡、增殖、周期、遷移、侵襲、修復(fù)、克隆形成)、細(xì)胞培養(yǎng)、細(xì)胞膜制備、穩(wěn)定細(xì)胞株構(gòu)建、細(xì)胞RNAi技術(shù)等等。