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產(chǎn)地 | 進(jìn)口、國產(chǎn) |
品牌 | 上海莼試 |
保存條件 | Store at -20 °C |
貨號 | CS9778 |
應(yīng)用范圍 | WB=1:100-500 ELISA=1:500-1000 IP=1:20-100 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 |
CAS編號 | |
抗體名 | Anti-Ninein/GSK3B interacting protein |
克隆性 | |
靶點 | 詳見說明書 |
適應(yīng)物種 | 詳見說明書 |
形態(tài) | 詳見說明書 |
宿主 | 詳見說明書 |
亞型 | IgG |
標(biāo)識物 | 詳見說明書 |
濃度 | 1mg/1ml% |
免疫原 | KLH conjugated synthetic peptide derived from human Ninein |
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GSK3B相互作用蛋白抗體規(guī)格 英文名稱 Anti-Ninein/GSK3B interacting protein
中文名稱 GSK3B相互作用蛋白抗體規(guī)格
別 名 Centrosome Marker; Glycogen synthase kinase 3 beta interacting protein; GSK3B interacting protein; hNinein; KIAA1565; NIN; NIN protein; Ninein centrosomal protein; NIN_HUMAN.
產(chǎn)品屬性:
濃 度 1mg/1ml
規(guī) 格 0.2ml/200μg
抗體來源 Rabbit
克隆類型 polyclonal
交叉反應(yīng) Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit
產(chǎn)品類型 一抗
研究領(lǐng)域 細(xì)胞生物 信號轉(zhuǎn)導(dǎo) 細(xì)胞周期蛋白
蛋白分子量 predicted molecular weight: 243kDa
性 狀 Lyophilized or Liquid
免 疫 原 KLH conjugated synthetic peptide derived from human Ninein
亞 型 IgG
純化方法 affinity purified by Protein A
儲 存 液 Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4
GSK3B相互作用蛋白抗體規(guī)格 產(chǎn)品應(yīng)用 WB=1:100-500 ELISA=1:500-1000 IP=1:20-100 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500
(石蠟切片需做抗原修復(fù))
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Important Note This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
產(chǎn)品介紹 Ninein is a centrosomal protein required for the positioning and anchorage of the microtubule minus-end in epithelial cells. It may also be a centrosome maturation factor and may be involved in microtubule nucleation. Ninein is a component of the core centrosome and is arranged in a tubular shape with an open and a closed end.
Function : Centrosomal protein required in the positioning and anchorage of the microtubule minus-end in epithelial cells. May also act as a centrosome maturation factor. May play a role in microtubule nucleation. Overexpression does not perturb nucleation or elongation of microtubules but suppresses release of microtubules.Subunit : Homooligomer. Interacts with GSK3B (GSK3-beta) via its C-terminus domain. Interacts with C14ORF166, such interaction may prevent its phosphorylation by GSK3-beta.Subcellular Location : Cytoplasm, cytoskeleton, centrosome.Tissue Specificity : Ubiquitous. Highly expressed in heart and skeletal muscle. Isoform 1 is more expressed than isoform 5.Post-translational modifications : Phosphorylated by Aurora A (AIK) and PKA kinases but not CK2 or Aurora B (AIM). Phosphorylated upon DNA damage, probably by ATM or ATR.Similarity : Contains 5 EF-hand domains.Database links : UniProtKB/Swiss-Prot: Q8N4C6.4
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